The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HM13-20-RE | 20 (40 μL) | 200 μL |  |
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| HM13-20-OR | 20 (40 μL) | 200 μL |  |
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| HM13-20-GO | 20 (40 μL) | 200 μL |  |
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| HM13-20-GR | 20 (40 μL) | 200 μL |  |
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| HM13-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : HM13
Gene Name : Histocompatibility minor 13
Chromosome : CHR 20: 315,144,09-315,695,66
Locus : 20q11.21
Alt. Genes : HIPK3
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