HIF1A FISH Probe

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
HIF1A-20-RE 20 (40 μL) 200 μL color Request Pricing
HIF1A-20-OR 20 (40 μL) 200 μL color Request Pricing
HIF1A-20-GO 20 (40 μL) 200 μL color Request Pricing
HIF1A-20-GR 20 (40 μL) 200 μL color Request Pricing
HIF1A-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]

Gene Details

Gene Symbol : HIF1A

Gene Name : Hypoxia inducible factor 1 alpha subunit

Chromosome : CHR 14: 616,954,00-617,482,58

Locus : 14q23.2

Alt. Genes : PREB

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