HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HERC4-20-RE | 20 (40 μL) | 200 μL |  |
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| HERC4-20-OR | 20 (40 μL) | 200 μL |  |
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| HERC4-20-GO | 20 (40 μL) | 200 μL |  |
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| HERC4-20-GR | 20 (40 μL) | 200 μL |  |
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| HERC4-20-AQ | 20 (40 μL) | 200 μL |  |
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HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]
Gene Symbol : HERC4
Gene Name : HECT and RLD domain containing E3 ubiquitin protein ligase 4
Chromosome : CHR 10: 680,753,47-679,218,98
Locus : 10q21.3
Alt. Genes : ENAM
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