The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
HAVCR2-20-RE | 20 (40 μL) | 200 μL | ![]() |
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HAVCR2-20-OR | 20 (40 μL) | 200 μL | ![]() |
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HAVCR2-20-GO | 20 (40 μL) | 200 μL | ![]() |
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HAVCR2-20-GR | 20 (40 μL) | 200 μL | ![]() |
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HAVCR2-20-AQ | 20 (40 μL) | 200 μL | ![]() |
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The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Gene Symbol : HAVCR2
Gene Name : Hepatitis A virus cellular receptor 2
Chromosome : CHR 5: 157,109,236-157,085,831
Locus : 5q33.3
Alt. Genes : LPCAT3
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