Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| H2BFWT-20-RE | 20 (40 μL) | 200 μL |  |
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| H2BFWT-20-OR | 20 (40 μL) | 200 μL |  |
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| H2BFWT-20-GO | 20 (40 μL) | 200 μL |  |
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| H2BFWT-20-GR | 20 (40 μL) | 200 μL |  |
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| H2BFWT-20-AQ | 20 (40 μL) | 200 μL |  |
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Oct 2015]
Gene Symbol : H2BFWT
Gene Name : H2B histone family member W, testis specific
Chromosome : CHR X: 104,013,686-104,011,146
Locus : Xq22.2
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