The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GTF3A-20-RE | 20 (40 μL) | 200 μL |  |
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| GTF3A-20-OR | 20 (40 μL) | 200 μL |  |
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| GTF3A-20-GO | 20 (40 μL) | 200 μL |  |
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| GTF3A-20-GR | 20 (40 μL) | 200 μL |  |
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| GTF3A-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Gene Symbol : GTF3A
Gene Name : General transcription factor IIIA
Chromosome : CHR 13: 274,245,43-274,357,08
Locus : 13q12.2
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