This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRAP2-20-RE | 20 (40 μL) | 200 μL |  |
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| GRAP2-20-OR | 20 (40 μL) | 200 μL |  |
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| GRAP2-20-GO | 20 (40 μL) | 200 μL |  |
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| GRAP2-20-GR | 20 (40 μL) | 200 μL |  |
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| GRAP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Symbol : GRAP2
Gene Name : GRB2-related adaptor protein 2
Chromosome : CHR 22: 399,010,72-399,733,42
Locus : 22q13.1
Alt. Genes : OPTN
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