This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPT-20-RE | 20 (40 μL) | 200 μL |  |
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| GPT-20-OR | 20 (40 μL) | 200 μL |  |
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| GPT-20-GO | 20 (40 μL) | 200 μL |  |
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| GPT-20-GR | 20 (40 μL) | 200 μL |  |
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| GPT-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
Gene Symbol : GPT
Gene Name : Glutamic--pyruvic transaminase
Chromosome : CHR 8: 144,502,216-144,507,173
Locus : 8q24.3
Alt. Genes : CEBPZ
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