The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPSM2-20-RE | 20 (40 μL) | 200 μL |  |
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| GPSM2-20-OR | 20 (40 μL) | 200 μL |  |
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| GPSM2-20-GO | 20 (40 μL) | 200 μL |  |
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| GPSM2-20-GR | 20 (40 μL) | 200 μL |  |
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| GPSM2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Symbol : GPSM2
Gene Name : G protein signaling modulator 2
Chromosome : CHR 1: 108,875,349-108,934,334
Locus : 1p13.3
Alt. Genes : PREB
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