Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GNAI3-20-RE | 20 (40 μL) | 200 μL |  |
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| GNAI3-20-OR | 20 (40 μL) | 200 μL |  |
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| GNAI3-20-GO | 20 (40 μL) | 200 μL |  |
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| GNAI3-20-GR | 20 (40 μL) | 200 μL |  |
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| GNAI3-20-AQ | 20 (40 μL) | 200 μL |  |
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Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012]
Gene Symbol : GNAI3
Gene Name : G protein subunit alpha i3
Chromosome : CHR 1: 109,548,563-109,595,842
Locus : 1p13.3
Alt. Genes : OPTN
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