This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLRB-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GLRB-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GLRB-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GLRB-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GLRB-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Symbol : GLRB
Gene Name : Glycine receptor beta
Chromosome : CHR 4: 157,076,124-157,172,089
Locus : 4q32.1
Alt. Genes : ZNF263
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.