This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLIPR1-20-RE | 20 (40 μL) | 200 μL |  |
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| GLIPR1-20-OR | 20 (40 μL) | 200 μL |  |
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| GLIPR1-20-GO | 20 (40 μL) | 200 μL |  |
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| GLIPR1-20-GR | 20 (40 μL) | 200 μL |  |
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| GLIPR1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : GLIPR1
Gene Name : GLI pathogenesis related 1
Chromosome : CHR 12: 754,807,32-755,019,35
Locus : 12q21.2
Alt. Genes : G3BP1
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