The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GGCT-20-RE | 20 (40 μL) | 200 μL |  |
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| GGCT-20-OR | 20 (40 μL) | 200 μL |  |
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| GGCT-20-GO | 20 (40 μL) | 200 μL |  |
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| GGCT-20-GR | 20 (40 μL) | 200 μL |  |
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| GGCT-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Symbol : GGCT
Gene Name : Gamma-glutamylcyclotransferase
Chromosome : CHR 7: 305,048,40-304,966,20
Locus : 7p14.3
Alt. Genes : YAF2
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