GDF7 FISH Probe

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
GDF7-20-RE 20 (40 μL) 200 μL color Request Pricing
GDF7-20-OR 20 (40 μL) 200 μL color Request Pricing
GDF7-20-GO 20 (40 μL) 200 μL color Request Pricing
GDF7-20-GR 20 (40 μL) 200 μL color Request Pricing
GDF7-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]

Gene Details

Gene Symbol : GDF7

Gene Name : Growth differentiation factor 7

Chromosome : CHR 2: 206,666,63-206,714,89

Locus : 2p24.1

Alt. Genes : ATP6AP2

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