This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GDF3-20-RE | 20 (40 μL) | 200 μL |  |
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| GDF3-20-OR | 20 (40 μL) | 200 μL |  |
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| GDF3-20-GO | 20 (40 μL) | 200 μL |  |
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| GDF3-20-GR | 20 (40 μL) | 200 μL |  |
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| GDF3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]
Gene Symbol : GDF3
Gene Name : Growth differentiation factor 3
Chromosome : CHR 12: 769,576,3-768,978,4
Locus : 12p13.31
Alt. Genes : SUGP2
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