This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GDF11-20-RE | 20 (40 μL) | 200 μL |  |
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| GDF11-20-OR | 20 (40 μL) | 200 μL |  |
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| GDF11-20-GO | 20 (40 μL) | 200 μL |  |
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| GDF11-20-GR | 20 (40 μL) | 200 μL |  |
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| GDF11-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]
Gene Symbol : GDF11
Gene Name : Growth differentiation factor 11
Chromosome : CHR 12: 557,432,77-557,571,93
Locus : 12q13.2
Alt. Genes : CEBPZ
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