The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GABBR2-20-RE | 20 (40 μL) | 200 μL |  |
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| GABBR2-20-OR | 20 (40 μL) | 200 μL |  |
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| GABBR2-20-GO | 20 (40 μL) | 200 μL |  |
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| GABBR2-20-GR | 20 (40 μL) | 200 μL |  |
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| GABBR2-20-AQ | 20 (40 μL) | 200 μL |  |
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The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
Gene Symbol : GABBR2
Gene Name : Gamma-aminobutyric acid type B receptor subunit 2
Chromosome : CHR 9: 987,091,96-982,880,81
Locus : 9q22.33
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