This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FUS-20-RE | 20 (40 μL) | 200 μL |  |
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| FUS-20-OR | 20 (40 μL) | 200 μL |  |
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| FUS-20-GO | 20 (40 μL) | 200 μL |  |
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| FUS-20-GR | 20 (40 μL) | 200 μL |  |
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| FUS-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
Gene Symbol : FUS
Gene Name : FUS RNA binding protein
Chromosome : CHR 16: 311,794,43-311,948,70
Locus : 16p11.2
Alt. Genes : OPTN
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