This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FSCN1-20-RE | 20 (40 μL) | 200 μL |  |
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| FSCN1-20-OR | 20 (40 μL) | 200 μL |  |
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| FSCN1-20-GO | 20 (40 μL) | 200 μL |  |
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| FSCN1-20-GR | 20 (40 μL) | 200 μL |  |
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| FSCN1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Gene Symbol : FSCN1
Gene Name : Fascin actin-bundling protein 1
Chromosome : CHR 7: 559,280,4-560,665,5
Locus : 7p22.1
Alt. Genes : OPTN
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