This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FREM2-20-RE | 20 (40 μL) | 200 μL |  |
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| FREM2-20-OR | 20 (40 μL) | 200 μL |  |
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| FREM2-20-GO | 20 (40 μL) | 200 μL |  |
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| FREM2-20-GR | 20 (40 μL) | 200 μL |  |
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| FREM2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014]
Gene Symbol : FREM2
Gene Name : FRAS1 related extracellular matrix protein 2
Chromosome : CHR 13: 386,870,35-388,871,30
Locus : 13q13.3
Alt. Genes : CLEC3A
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