The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FKBP3-20-RE | 20 (40 μL) | 200 μL |  |
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| FKBP3-20-OR | 20 (40 μL) | 200 μL |  |
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| FKBP3-20-GO | 20 (40 μL) | 200 μL |  |
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| FKBP3-20-GR | 20 (40 μL) | 200 μL |  |
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| FKBP3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]
Gene Symbol : FKBP3
Gene Name : FK506 binding protein 3
Chromosome : CHR 14: 451,345,28-451,155,98
Locus : 14q21.2
Alt. Genes : MKRN3-AS1
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