The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EZR-20-RE | 20 (40 μL) | 200 μL |  |
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| EZR-20-OR | 20 (40 μL) | 200 μL |  |
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| EZR-20-GO | 20 (40 μL) | 200 μL |  |
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| EZR-20-GR | 20 (40 μL) | 200 μL |  |
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| EZR-20-AQ | 20 (40 μL) | 200 μL |  |
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The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : EZR
Gene Name : Ezrin
Chromosome : CHR 6: 158,819,423-158,765,740
Locus : 6q25.3
Alt. Genes : YAF2
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