This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EXOSC1-20-RE | 20 (40 μL) | 200 μL |  |
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| EXOSC1-20-OR | 20 (40 μL) | 200 μL |  |
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| EXOSC1-20-GO | 20 (40 μL) | 200 μL |  |
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| EXOSC1-20-GR | 20 (40 μL) | 200 μL |  |
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| EXOSC1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Symbol : EXOSC1
Gene Name : Exosome component 1
Chromosome : CHR 10: 974,460,64-974,359,08
Locus : 10q24.1
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