This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERCC3-20-RE | 20 (40 μL) | 200 μL |  |
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| ERCC3-20-OR | 20 (40 μL) | 200 μL |  |
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| ERCC3-20-GO | 20 (40 μL) | 200 μL |  |
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| ERCC3-20-GR | 20 (40 μL) | 200 μL |  |
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| ERCC3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Symbol : ERCC3
Gene Name : ERCC excision repair 3, TFIIH core complex helicase subunit
Chromosome : CHR 2: 127,294,175-127,257,289
Locus : 2q14.3
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