This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EPX-20-RE | 20 (40 μL) | 200 μL |  |
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| EPX-20-OR | 20 (40 μL) | 200 μL |  |
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| EPX-20-GO | 20 (40 μL) | 200 μL |  |
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| EPX-20-GR | 20 (40 μL) | 200 μL |  |
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| EPX-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]
Gene Symbol : EPX
Gene Name : Eosinophil peroxidase
Chromosome : CHR 17: 581,927,23-582,051,73
Locus : 17q22
Alt. Genes : LINC01587
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