This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EML4-20-RE | 20 (40 μL) | 200 μL |  |
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| EML4-20-OR | 20 (40 μL) | 200 μL |  |
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| EML4-20-GO | 20 (40 μL) | 200 μL |  |
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| EML4-20-GR | 20 (40 μL) | 200 μL |  |
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| EML4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]
Gene Symbol : EML4
Gene Name : Echinoderm microtubule associated protein like 4
Chromosome : CHR 2: 421,693,37-423,325,47
Locus : 2p21
Alt. Genes : LRPPRC
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