EIF4G1 FISH Probe

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
EIF4G1-20-RE 20 (40 μL) 200 μL color Request Pricing
EIF4G1-20-OR 20 (40 μL) 200 μL color Request Pricing
EIF4G1-20-GO 20 (40 μL) 200 μL color Request Pricing
EIF4G1-20-GR 20 (40 μL) 200 μL color Request Pricing
EIF4G1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]

Gene Details

Gene Symbol : EIF4G1

Gene Name : Eukaryotic translation initiation factor 4 gamma 1

Chromosome : CHR 3: 184,314,494-184,335,357

Locus : 3q27.1

Alt. Genes : ZNF263

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