This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EI24-20-RE | 20 (40 μL) | 200 μL |  |
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| EI24-20-OR | 20 (40 μL) | 200 μL |  |
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| EI24-20-GO | 20 (40 μL) | 200 μL |  |
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| EI24-20-GR | 20 (40 μL) | 200 μL |  |
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| EI24-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014]
Gene Symbol : EI24
Gene Name : EI24, autophagy associated transmembrane protein
Chromosome : CHR 11: 125,569,215-125,584,688
Locus : 11q24.2
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