Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DUSP10-20-RE | 20 (40 μL) | 200 μL |  |
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| DUSP10-20-OR | 20 (40 μL) | 200 μL |  |
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| DUSP10-20-GO | 20 (40 μL) | 200 μL |  |
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| DUSP10-20-GR | 20 (40 μL) | 200 μL |  |
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| DUSP10-20-AQ | 20 (40 μL) | 200 μL |  |
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Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Symbol : DUSP10
Gene Name : Dual specificity phosphatase 10
Chromosome : CHR 1: 221,742,175-221,701,419
Locus : 1q41
Alt. Genes : PREB
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