This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DSG3-20-RE | 20 (40 μL) | 200 μL |  |
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| DSG3-20-OR | 20 (40 μL) | 200 μL |  |
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| DSG3-20-GO | 20 (40 μL) | 200 μL |  |
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| DSG3-20-GR | 20 (40 μL) | 200 μL |  |
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| DSG3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
Gene Symbol : DSG3
Gene Name : Desmoglein 3
Chromosome : CHR 18: 314,477,68-314,787,01
Locus : 18q12.1
Alt. Genes : LPAR6
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