This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DLEU2-20-RE | 20 (40 μL) | 200 μL |  |
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| DLEU2-20-OR | 20 (40 μL) | 200 μL |  |
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| DLEU2-20-GO | 20 (40 μL) | 200 μL |  |
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| DLEU2-20-GR | 20 (40 μL) | 200 μL |  |
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| DLEU2-20-AQ | 20 (40 μL) | 200 μL |  |
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This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017]
Gene Symbol : DLEU2
Gene Name : Deleted in lymphocytic leukemia 2 (non-protein coding)
Chromosome : CHR 13: 501,255,40-499,825,51
Locus : 13q14.2
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