This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DLC1-20-RE | 20 (40 μL) | 200 μL |  |
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| DLC1-20-OR | 20 (40 μL) | 200 μL |  |
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| DLC1-20-GO | 20 (40 μL) | 200 μL |  |
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| DLC1-20-GR | 20 (40 μL) | 200 μL |  |
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| DLC1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
Gene Symbol : DLC1
Gene Name : DLC1 Rho GTPase activating protein
Chromosome : CHR 8: 136,046,05-130,833,60
Locus : 8p22
Alt. Genes : FARP1
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