This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DISC1-20-RE | 20 (40 μL) | 200 μL |  |
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| DISC1-20-OR | 20 (40 μL) | 200 μL |  |
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| DISC1-20-GO | 20 (40 μL) | 200 μL |  |
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| DISC1-20-GR | 20 (40 μL) | 200 μL |  |
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| DISC1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : DISC1
Gene Name : Disrupted in schizophrenia 1
Chromosome : CHR 1: 231,626,814-232,041,271
Locus : 1q42.2
Alt. Genes : FAM13A
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