DEFA5 FISH Probe

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Oct 2014]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
DEFA5-20-RE 20 (40 μL) 200 μL color Request Pricing
DEFA5-20-OR 20 (40 μL) 200 μL color Request Pricing
DEFA5-20-GO 20 (40 μL) 200 μL color Request Pricing
DEFA5-20-GR 20 (40 μL) 200 μL color Request Pricing
DEFA5-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Oct 2014]

Gene Details

Gene Symbol : DEFA5

Gene Name : Defensin alpha 5

Chromosome : CHR 8: 705,673,8-705,529,9

Locus : 8p23.1

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