This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCLRE1C-20-RE | 20 (40 μL) | 200 μL |  |
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| DCLRE1C-20-OR | 20 (40 μL) | 200 μL |  |
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| DCLRE1C-20-GO | 20 (40 μL) | 200 μL |  |
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| DCLRE1C-20-GR | 20 (40 μL) | 200 μL |  |
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| DCLRE1C-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Symbol : DCLRE1C
Gene Name : DNA cross-link repair 1C
Chromosome : CHR 10: 149,544,31-148,978,52
Locus : 10p13
Alt. Genes : RBM12
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