DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DAD1-20-RE | 20 (40 μL) | 200 μL |  |
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| DAD1-20-OR | 20 (40 μL) | 200 μL |  |
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| DAD1-20-GO | 20 (40 μL) | 200 μL |  |
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| DAD1-20-GR | 20 (40 μL) | 200 μL |  |
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| DAD1-20-AQ | 20 (40 μL) | 200 μL |  |
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DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]
Gene Symbol : DAD1
Gene Name : Defender against cell death 1
Chromosome : CHR 14: 225,892,36-225,649,06
Locus : 14q11.2
Alt. Genes : MKRN3-AS1
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