CYP26B1 FISH Probe

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
CYP26B1-20-RE 20 (40 μL) 200 μL color Request Pricing
CYP26B1-20-OR 20 (40 μL) 200 μL color Request Pricing
CYP26B1-20-GO 20 (40 μL) 200 μL color Request Pricing
CYP26B1-20-GR 20 (40 μL) 200 μL color Request Pricing
CYP26B1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

Gene Details

Gene Symbol : CYP26B1

Gene Name : Cytochrome P450 family 26 subfamily B member 1

Chromosome : CHR 2: 721,478,61-721,292,37

Locus : 2p13.2

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