This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP11B2-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP11B2-20-OR | 20 (40 μL) | 200 μL |  |
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| CYP11B2-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP11B2-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP11B2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
Gene Symbol : CYP11B2
Gene Name : Cytochrome P450 family 11 subfamily B member 2
Chromosome : CHR 8: 142,917,842-142,910,558
Locus : 8q24.3
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