CTNND2 FISH Probe

This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
CTNND2-20-RE 20 (40 μL) 200 μL color Request Pricing
CTNND2-20-OR 20 (40 μL) 200 μL color Request Pricing
CTNND2-20-GO 20 (40 μL) 200 μL color Request Pricing
CTNND2-20-GR 20 (40 μL) 200 μL color Request Pricing
CTNND2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

Gene Details

Gene Symbol : CTNND2

Gene Name : Catenin delta 2

Chromosome : CHR 5: 119,040,66-109,718,39

Locus : 5p15.2

Alt. Genes : YAF2

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