The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COPS8-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| COPS8-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| COPS8-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| COPS8-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| COPS8-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Gene Symbol : COPS8
Gene Name : COP9 signalosome subunit 8
Chromosome : CHR 2: 237,085,440-237,098,845
Locus : 2q37.3
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.