In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CNGB1-20-RE | 20 (40 μL) | 200 μL |  |
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| CNGB1-20-OR | 20 (40 μL) | 200 μL |  |
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| CNGB1-20-GO | 20 (40 μL) | 200 μL |  |
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| CNGB1-20-GR | 20 (40 μL) | 200 μL |  |
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| CNGB1-20-AQ | 20 (40 μL) | 200 μL |  |
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In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Gene Symbol : CNGB1
Gene Name : Cyclic nucleotide gated channel beta 1
Chromosome : CHR 16: 579,711,15-578,823,39
Locus : 16q21
Alt. Genes : TRIM28
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