This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CLSTN1-20-RE | 20 (40 μL) | 200 μL |  |
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| CLSTN1-20-OR | 20 (40 μL) | 200 μL |  |
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| CLSTN1-20-GO | 20 (40 μL) | 200 μL |  |
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| CLSTN1-20-GR | 20 (40 μL) | 200 μL |  |
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| CLSTN1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Symbol : CLSTN1
Gene Name : Calsyntenin 1
Chromosome : CHR 1: 982,452,5-972,902,0
Locus : 1p36.22
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