The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHRM3-20-RE | 20 (40 μL) | 200 μL |  |
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| CHRM3-20-OR | 20 (40 μL) | 200 μL |  |
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| CHRM3-20-GO | 20 (40 μL) | 200 μL |  |
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| CHRM3-20-GR | 20 (40 μL) | 200 μL |  |
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| CHRM3-20-AQ | 20 (40 μL) | 200 μL |  |
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The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Gene Symbol : CHRM3
Gene Name : Cholinergic receptor muscarinic 3
Chromosome : CHR 1: 239,386,564-239,915,449
Locus : 1q43
Alt. Genes : OPTN
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