CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHMP4C-20-RE | 20 (40 μL) | 200 μL |  |
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| CHMP4C-20-OR | 20 (40 μL) | 200 μL |  |
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| CHMP4C-20-GO | 20 (40 μL) | 200 μL |  |
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| CHMP4C-20-GR | 20 (40 μL) | 200 μL |  |
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| CHMP4C-20-AQ | 20 (40 μL) | 200 μL |  |
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CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
Gene Symbol : CHMP4C
Gene Name : Charged multivesicular body protein 4C
Chromosome : CHR 8: 817,324,52-817,595,14
Locus : 8q21.13
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