This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHAC1-20-RE | 20 (40 μL) | 200 μL |  |
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| CHAC1-20-OR | 20 (40 μL) | 200 μL |  |
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| CHAC1-20-GO | 20 (40 μL) | 200 μL |  |
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| CHAC1-20-GR | 20 (40 μL) | 200 μL |  |
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| CHAC1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016]
Gene Symbol : CHAC1
Gene Name : ChaC glutathione specific gamma-glutamylcyclotransferase 1
Chromosome : CHR 15: 409,421,34-409,565,18
Locus : 15q15.1
Alt. Genes : RAD50
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