The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CENPU-20-RE | 20 (40 μL) | 200 μL |  |
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| CENPU-20-OR | 20 (40 μL) | 200 μL |  |
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| CENPU-20-GO | 20 (40 μL) | 200 μL |  |
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| CENPU-20-GR | 20 (40 μL) | 200 μL |  |
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| CENPU-20-AQ | 20 (40 μL) | 200 μL |  |
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The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]
Gene Symbol : CENPU
Gene Name : Centromere protein U
Chromosome : CHR 4: 184,734,131-184,694,064
Locus : 4q35.1
Alt. Genes : RBM12
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