CDC73 FISH Probe

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
CDC73-20-RE 20 (40 μL) 200 μL color Request Pricing
CDC73-20-OR 20 (40 μL) 200 μL color Request Pricing
CDC73-20-GO 20 (40 μL) 200 μL color Request Pricing
CDC73-20-GR 20 (40 μL) 200 μL color Request Pricing
CDC73-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

Gene Details

Gene Symbol : CDC73

Gene Name : Cell division cycle 73

Chromosome : CHR 1: 193,121,957-193,254,814

Locus : 1q31.2

Alt. Genes : LRPPRC

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