The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDC16-20-RE | 20 (40 μL) | 200 μL |  |
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| CDC16-20-OR | 20 (40 μL) | 200 μL |  |
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| CDC16-20-GO | 20 (40 μL) | 200 μL |  |
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| CDC16-20-GR | 20 (40 μL) | 200 μL |  |
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| CDC16-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jan 2016]
Gene Symbol : CDC16
Gene Name : Cell division cycle 16
Chromosome : CHR 13: 114,234,844-114,272,674
Locus : 13q34
Alt. Genes : ZNF263
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