This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD4-20-RE | 20 (40 μL) | 200 μL |  |
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| CD4-20-OR | 20 (40 μL) | 200 μL |  |
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| CD4-20-GO | 20 (40 μL) | 200 μL |  |
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| CD4-20-GR | 20 (40 μL) | 200 μL |  |
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| CD4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
Gene Symbol : CD4
Gene Name : CD4 molecule
Chromosome : CHR 12: 678,947,1-682,080,9
Locus : 12p13.31
Alt. Genes : PLXNC1
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