This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CASP8AP2-20-RE | 20 (40 μL) | 200 μL |  |
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| CASP8AP2-20-OR | 20 (40 μL) | 200 μL |  |
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| CASP8AP2-20-GO | 20 (40 μL) | 200 μL |  |
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| CASP8AP2-20-GR | 20 (40 μL) | 200 μL |  |
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| CASP8AP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
Gene Symbol : CASP8AP2
Gene Name : Caspase 8 associated protein 2
Chromosome : CHR 6: 898,298,99-898,744,35
Locus : 6q15
Alt. Genes : FEM1B
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